Spray drying pharmaceuticals
Detailed introduction to spray drying drugs
- Formulation Preparation: Pharmaceuticals, such as drugs and active pharmaceutical ingredients (APIs), are formulated in a liquid or semi-solid form, which needs to be converted into a dry powder for various applications.
- Atomization Process: In the spray drying process, the liquid or semi-solid feed is atomized into fine droplets using high-pressure nozzles or rotary atomizers.
- Contact with Hot Air: The atomized droplets are introduced into a drying chamber where they come into contact with hot air or gas, causing the rapid evaporation of moisture.
- Drying and Particle Formation: As the droplets travel through the drying chamber, the moisture evaporates, leaving behind dry particles that are collected at the bottom of the chamber.
- Controlled Conditions: The spray drying process is carefully controlled to ensure the desired particle size, moisture content, and other characteristics of the final product.
- Applications: Spray drying is used in the pharmaceutical industry to produce drug formulations, excipients, inhalable powders, and other pharmaceutical products.
.Advantages of spray drying pharmaceuticals
- Uniform Particle Size: Spray drying produces particles with consistent size distribution, which is crucial for ensuring dosage uniformity in pharmaceutical formulations.
- Increased Solubility: Spray drying can be used to produce amorphous forms of drugs, which are often more soluble and bioavailable than their crystalline counterparts.
- Controlled Release: Spray drying allows for the encapsulation of drugs in microspheres or nanoparticles, which can provide controlled drug release, enhancing efficacy and reducing side effects.
- Improved Stability: Spray drying can help stabilize sensitive drugs by removing moisture, which can reduce degradation and increase shelf life.
- Easy Scale-Up: The spray drying process is relatively easy to scale up from laboratory to industrial production, allowing for efficient and cost-effective manufacturing.
- Versatility: Spray drying can be used with a wide range of pharmaceutical ingredients, including small molecules, peptides, proteins, and lipids, making it a versatile option for drug formulation.
Application areas
- Industry: chemical,pharmaceutical,food,dehydrated vegetables,grain,mining,etc
Application: aslemon Acid,chicken essence,borax,ammonium sulfate,radish silk,seeds,salt,silkworm, etc
Technical Parameters
MODEL | EVAPORATION CAPACITY (L/H) | HEATING SOURCE | SPRAY HEAD ROTATION FORM | SPRAY HEAD ROTATION SPEED | DIMENSION |
GRT-LPG5 | 5 | ELECTRICITY | COMPRESSED AIR DRIVE | 25000 RPM | 1.8*0.93*2.2M |
GRT-LPG10 | 10 | ELECTRICITY | COMPRESSED AIR DRIVE | 20000 RPM | 2.0*0.95*2.25M |
GRT-LPG25 | 25 | ELECTRICITY/STEAM/GAS/OIL | MECHANICAL TRANSMISSION | 18000 RPM | 3*2.7*4.26M |
GRT-LPG50 | 50 | ELECTRICITY/STEAM/GAS/OIL | MECHANICAL TRANSMISSION | 18000 RPM | 3.7*3.2*5.1M |
GRT-LPG100 | 100 | ELECTRICITY/STEAM/GAS/OIL | MECHANICAL TRANSMISSION | 18000 RPM | 4.6*4.2*6.0M |
GRT-LPG150 | 150 | ELECTRICITY/STEAM/GAS/OIL | MECHANICAL TRANSMISSION | 15000 RPM | 5.5*4.5*7M |